The optimization of production and operation parameters of oil pipelines can effectively reduce operation energy consumption and improve the economic benefits of pipeline transportation. Aiming at the newly⁃built Qingha oil pipeline in the high and cold regions,the production energy optimization model was established with the constraints of the minimum energy consumption in production and operation,and the constraints of temperature constraints,pressure constraints,and oil pump operating characteristics constraints.In order to improve the solution efficiency,the hybrid PSO⁃Powell algorithm is used to solve the problem.The optimization results show that after optimization,the thermal energy loss is reduced by 38.3%,the pressure energy loss is increased by 90.3%,and the total energy loss is reduced by 26.3%.The energy saving effect is obvious.